Adipocyte size is associated with NAFLD independent of obesity, fat distribution, and PNPLA3 genotype
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چکیده
منابع مشابه
Visceral Adipocyte Hypertrophy is Associated With Dyslipidemia Independent of Body Composition and Fat Distribution in Women
OBJECTIVE We assessed whether subcutaneous and omental adipocyte hypertrophy are related to metabolic alterations independent of body composition and fat distribution in women. RESEARCH DESIGN AND METHODS Mean adipocyte diameter of paired subcutaneous and omental adipose tissue samples was obtained in lean to obese women. Linear regression models predicting adipocyte size in both adipose tiss...
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BACKGROUND Both body fat distribution and adipocyte size are associated with metabolic abnormalities. OBJECTIVE We defined the extent to which subcutaneous adipocyte size is related to regional fat mass and to the sizes of adipocytes in other subcutaneous depots independent of adiposity, age, and sex. DESIGN Data collected from 188 women and 133 men who were 18-50 y old and who had a body m...
متن کاملCirculating triacylglycerol signatures in nonalcoholic fatty liver disease associated with the I148M variant in PNPLA3 and with obesity.
We examined whether relative concentrations of circulating triacylglycerols (TAGs) between carriers compared with noncarriers of PNPLA3(I148M) gene variant display deficiency of TAGs, which accumulate in the liver because of defective lipase activity. We also analyzed the effects of obesity-associated nonalcoholic fatty liver disease (NAFLD) independent of genotype, and of NAFLD due to either P...
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Background: The prevalence of obesity is increasing and many countries are struggling with its high rate and serious complications. As a result of distinct diet in obese children, they may be susceptible to nutritional deficiencies in particular, iron deficiency. This study aimed to examine the relationship between obesity and iron indices. Methods: In this cross-sectional study, 206 element...
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ژورنال
عنوان ژورنال: Obesity
سال: 2013
ISSN: 1930-7381
DOI: 10.1002/oby.20114